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Anti-Human Complement Component 3 (C3)

C3 is active in both the classic and alternative complement pathways where it activates factors involved in the lysis of red cells and various pathogens.  Decreased levels are seen in autoimmune diseases due to complement activation or diminished synthesis.  Deficiencies of C3 are common in severe infections and with increased risk for systemic lupus erythematosus.

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